Species Human Entrez 923 | Human Mouse Ensembl ENSG00000013725 | |
Aliases CD6, TP120, CD6 molecule External IDs MGI: 103566 HomoloGene: 4893 GeneCards: CD6 | ||
CD6 (Cluster of Differentiation 6) is a human protein encoded by the CD6 gene.
Contents
Function
This gene encodes a protein found on the outer membrane of T-lymphocytes as well as some other immune cells. The encoded protein contains three scavenger receptor cysteine-rich (SRCR) domains and a binding site for an activated leukocyte cell adhesion molecule. The gene product is important for continuation of T cell activation.
Clinical significance
Certain alleles of this gene may be associated with susceptibility to multiple sclerosis.
References
CD6 Wikipedia(Text) CC BY-SA