Entrez 53339 | Ensembl ENSG00000064726 | |
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Aliases BTBD1, C15orf1, NS5ATP8, BTB domain containing 1 External IDs MGI: 1933765 HomoloGene: 23529 GeneCards: BTBD1 | ||
BTB/POZ domain-containing protein 1 is a protein that in humans is encoded by the BTBD1 gene.
Contents
Function
The C-terminus of the protein encoded by this gene binds topoisomerase I. The N-terminus contains a proline-rich region and a BTB/POZ domain (broad-complex, Tramtrack and bric a brac/Pox virus and Zinc finger), both of which are typically involved in protein-protein interactions. Subcellularly, the protein localizes to cytoplasmic bodies. Alternative splicing results in multiple transcript variants encoding different isoforms.
Interactions
BTBD1 has been shown to interact with TOP1.
References
BTBD1 Wikipedia(Text) CC BY-SA