ATC code J01CA09 (WHO) PubChem CID 6479523 ChemSpider 4980416 CAS ID 37091-66-0 | CAS Number 37091-66-0 DrugBank DB01061 Molar mass 461.491 g/mol | |
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AHFS/Drugs.com International Drug Names | ||
Azlocillin is an acylampicillin antibiotic with an extended spectrum of activity and greater in vitro potency than the carboxy penicillins. Azlocillin is similar to mezlocillin and piperacillin. It demonstrates antibacterial activity against a broad spectrum of bacteria, including Pseudomonas aeruginosa and, in contrast to most cephalosporins, exhibits activity against enterococci.
Contents
Medical vocabulary what does azlocillin mean
Spectrum of bacterial susceptibility
Azlocillin is considered a broad spectrum antibiotic and can be used against a number of Gram positive and Gram negative bacteria. The following represents MIC susceptibility data for a few medically significant organisms.
Synthesis
An interesting alternative synthesis of azlocillin involves activation of the substituted phenylglycine analogue 1 with 1,3-dimethyl-2-chloro-1-imidazolinium chloride (2) and then condensation with 6-APA.
