Ayres is a surname. Notable people with the surname include:
Agnes Ayres (1898–1940), American silent film actorAlice Ayres (1859–1885), honored for rescuing of her three nieces from a burning building at the cost of her own lifeAnne Ayres (1816–1886), American Episcopalian nunBenjamin Ayres (born 1977) an actor, director, photographerBenjamin Ayres (instrument maker) (died c. 1775), an English instrument makerBill Ayres, American radio talk show host, co-founder and executive director of World Hunger YearCaroline Ayres, basketball playerChristopher Ayres (born 1965), American voice actorGary Ayres (born 1960), Australian rules footballer and coachGillian Ayres (born 1930), British painterGreg Ayres (born 1968), American voice actorH. Welborn Ayres (1900-1985), American judgeIan Ayres (born 1959), American professor at Yale Law School and Yale School of ManagementIan Ayres (filmmaker), American filmmakerJoão Maria Correia Ayres de Campos, 1st Count of Ameal (1847–1920), Portuguese humanist, politician and art-collectorJosé Márcio Ayres (1954–2003), Brazilian primatologist and conservationistLeonard Porter Ayres (1879–1946), American statisticianLew Ayres (1908–1996), American actorLewis Ayres, lay Catholic theologianPam Ayres (born 1947), British writer of humorous poetryPhilip Ayres (poet) (1638–1712), English poetPhilip Burnard Ayres, British physician and botanistRichard Ayres (born 1965), British composerRobert Ayres (disambiguation), multiple peopleRomeyn B. Ayres (1825–1888), Union general in the American Civil WarRosalind Ayres (born 1946), British actressThomas Ayres (1816–1858), artist who first drew YosemiteThomas Ayres (1828–1913), South African ornithologistVernon Ayres (born 1909), Canadian ice hockey playerWilliam Orville Ayres (1817–1887), American physician and ichthyologist