Group Group II (ssDNA) Subfamily Parvovirinae | Family Parvoviridae Rank Genus | |
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Aveparvovirus is a genus of viruses, in the family Parvoviridae, in the subfamily Parvovirinae. There is currently only one species in this genus: the type species Galliform aveparvovirus 1. At present the only known hosts are turkeys and chickens. Diseases associated with this genus include: enteric disease and malabsorption syndrome.
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Structure
Viruses in Aveparvovirus are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 18-26 nm. Genomes are linear, around 6kb in length.
Life Cycle
Viral replication is nuclear. Entry into the host cell is achieved by attachment to host receptors, and is probably driven by clathrin-mediated endocytosis. Replication follows the rolling-hairpin model. DNA-templated transcription, with some alternative splicing mechanism is the method of transcription. Its cell exit strategy remains to be determined but probably involves cell lysis, as seen for other parvoviruses,. Birds serve as the natural host.