Trisha Shetty

Arginine N succinyltransferase

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EC number
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  99676-48-9
KEGG  KEGG entry

In enzymology, an arginine N-succinyltransferase (EC is an enzyme that catalyzes the chemical reaction

succinyl-CoA + L-arginine CoA + N2-succinyl-L-arginine

Thus, the two substrates of this enzyme are succinyl-CoA and L-arginine, whereas its two products are CoA and N2-succinyl-L-arginine.

This enzyme belongs to the family of transferases, specifically those acyltransferases transferring groups other than aminoacyl groups. The systematic name of this enzyme class is succinyl-CoA:L-arginine N2-succinyltransferase. Other names in common use include arginine succinyltransferase, AstA, arginine and ornithine N2-succinyltransferase, AOST, AST, and succinyl-CoA:L-arginine 2-N-succinyltransferase. This enzyme participates in arginine and proline metabolism.

Structural studies

As of late 2007, only one structure has been solved for this class of enzymes, with the PDB accession code 1YLE.


Arginine N-succinyltransferase Wikipedia

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