EC number 3.4.24.83 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 477950-41-7 BRENDA BRENDA entry KEGG KEGG entry | |
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Anthrax lethal factor endopeptidase (EC 3.4.24.83, lethal toxin) is an enzyme that catalyzes the hydrolysis of mitogen-activated protein kinase kinases. This enzyme is a component of the lethal factor produced by the bacterium Bacillus anthracis. The preferred cleavage site can be denoted by BBBBxHxH, in which B denotes a basic amino acid Arg or Lys, H denotes a hydrophobic amino acid, and x is any amino acid.
References
Anthrax lethal factor endopeptidase Wikipedia(Text) CC BY-SA