Androstane is a C19 steroid with a gonane core. Androstane can exist as either of two isomers, known as 5α-androstane and 5β-androstane.
Androstanes
Androstanol3α,5α-Androstanol (5α-androstan-3α-ol) – an endogenous CAR antagonist3α,5β-Androstanol (5α-androstan-3β-ol) – an endogenous CAR antagonist5α,17-Androstanol (5α-androstan-17-ol) – an endogenous CAR antagonistAndrostanone5α-Androstanone (5α-androstan-3-one)Androstanediol3α-Androstanediol (5α-androstane-3α,17β-diol) – an endogenous androgen, estrogen, and neurosteroid3β-Androstanediol (5α-androstane-3β,17β-diol) – an endogenous estrogenAndrostanedione5α-Androstanedione (5α-androstane-3,17-dione)5β-Androstanedione (5β-androstane-3,17-dione)AndrostanoloneDihydrotestosterone (5α-androstan-17β-ol-3-one) – an endogenous androgen5β-Dihydrotestosterone (5β-androstan-17β-ol-3-one)Androsterone (5α-androstan-3α-ol-17-one) – an endogenous androgen and neurosteroidEpiandrosterone (5α-androstan-3β-ol-17-one) – an endogenous androgenEtiocholanolone (5β-androstan-3α-ol-17-one) – an endogenous neurosteroidEpietiocholanolone (5β-androstan-3β-ol-17-one)Androstenes
Androstenol3α,5α-Androstenol (5α-androst-16-en-3α-ol) – an endogenous pheromone, neurosteroid, and CAR antagonist3β,5α-Androstenol (5α-androst-16-en-3β-ol) – an endogenous pheromoneAndrostenone5α-Androstenone (5α-androst-16-en-3-one) – an endogenous pheromoneAndrostenediolΔ5-Androstenediol (Δ5-androsten-3β,17β-diol) – an endogenous androgen, estrogen, and testosterone intermediateΔ4-Androstenediol (Δ4-androsten-3β,17β-diol) – an androgen and testosterone prodrugΔ1-Androstenediol (Δ1-androsten-3β,17β-diol) – an androgen and δ1-testosterone prodrugAndrostenedioneΔ4-Androstenedione (Δ4-androsten-3,17-dione) – an endogenous androgen and testosterone intermediateΔ5-Androstenedione (Δ5-androsten-3,17-dione) – an androgen and testosterone prodrugΔ1-Androstenedione (Δ1-androsten-3,17-dione) – an androgen and δ1-testosterone prodrugAndrostenetrioneδ4-Androstenetrione (δ4-androstene-3,6,17-trione) – an aromatase inhibitorAndrostenoloneTestosterone (δ4-androsten-17β-ol-3-one) – an endogenous androgenδ1-Testosterone (δ1-androsten-17β-ol-3-one) – an androgenEpitestosterone (δ4-androsten-17α-ol-3-one) – an inactive steroidDehydroepiandrosterone (δ5-androsten-3β-ol-17-one) – an endogenous androgen, neurosteroid, agonist of PPARα, PXR, and CAR, and testosterone intermediateAndrostadienes
Androstadienolδ5-Androstadienol (δ5,16-androstadien-3β-ol) – an endogenous pheromoneδ4-Androstadienol (δ4,16-androstadien-3β-ol) – a synthetic pherineAndrostadienoneδ4-Androstadienone (δ4,16-androstadien-3-one) – an endogenous pheromoneSynthetic androgens and anabolic steroids are androstane derivatives.
Some progestins, such as ethisterone and dimethisterone, are also androstane derivatives.
