Born in Reggio Emilia, Galuppo started his professional career at Emilian club Parma F.C.. Since 2005–06 season he was loaned to various Serie C1 club. He only played once for Ancona before his loan was terminated. In January 2008 Galuppo left for Serie C2 club Carpenedolo. Galuppo returned to the Italian third division for Venezia in 2008–09 Lega Pro Prima Divisione. In January 2009 he made his Serie B debut for league struggler Treviso. Galuppo spent 2009–10 Lega Pro Prima Divisione for Cremonese.
In June 2010, few days before the closure of 2009–10 financial year, he was exchanged with Milan Đurić in co-ownership deal. Both players' 50% registration rights were valued €1.1 million, thus both clubs got a paper profit as it intangible asset increased (the new value of the player contract, as youth product did not had any historic cost value to form that asset). However, Cesena never able to benefit from the player in the football field as Galuppo was loaned out with disappointing performance (3 games a season), instead, benefited financially.
Galuppo left for Atletico Roma on 31 August 2010, re-joining other Parma team-mate in temporary deal in 2010–11 season.
After Marco Rossi joined Cesena in June 2011 in co-ownership deal for €2 million, Galuppo returned to Parma in July for €1 million. Galuppo was loaned out again for Foligno.
In June 2012, Parma made swap deals with other clubs again, which saw Manuel Coppola (€1.6 million), Galuppo (€1.7M), Abdou Doumbia (€0.5M) and Dellafiore (€1.8M) moved to Siena; Andrea Rossi (€1.8M), Alessandro Iacobucci (€1.7M), Gonçalo Brandão (€1.6M) and Giuseppe Pacini (€0.5M) to Parma. The move meant Parma did not have any cost generated from Galuppo in the 2011–12 financial year as the amortization of his transfer fee was totally outweighed by the profit. However it created another transfer fee to be amortized in 2012–13 accounts and beyond.
Both clubs did not announced the deal in their website and Galuppo, along with Doumbia and Parma team-mate Diego Mella, left for San Marino Calcio in another temporary deal.
Galuppo made his debut as starting centre-back on 5 August 2012, a 2012–13 Coppa Italia match.
On 27 July 2013 he was loaned to Savona.
He suffered a knee injury in October 2013.
Galuppo returned to Parma again on 18 June 2014, with Gonçalo Brandão moved back to Siena. Both 50% registration rights of the players were tagged for €1.1 million. In August 2014 he was signed by Gubbio in another temporary deal.
In summer 2015 Galuppo was signed by Serie D club Lentigione.