Rank Species | Division Firmicutes Order Acholeplasmatales | |
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Similar Acholeplasma, Mycoplasma hyorhinis, Mycoplasma fermentans, Mollicutes, Spiroplasma | ||
Medical vocabulary what does acholeplasma laidlawii mean
Acholeplasma laidlawii are small bacteria which lack a cell wall. Like other Acholeplasma and Mycoplasma, A. laidlawii has been identified as a common contaminant of growth media for cell culture.
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History
A. laidlawii was first isolated from sewage in London in 1936 and was named after its discoverer, Patrick Laidlaw.
Genetics
A. laidlawii has a relatively small genome comprising 1.5Mbp. Additionally its genome has a low GC-content of just 31%. The A. laidlawii genome has been sequenced.
In Research
Acholeplasma laidlawii may contaminate bovine serum and also occurs in serum-free cell culture media products. The presence of A. laidlawii in broth powders is a serious problem in routine biopharmaceutical operations where filtration is used as a sterilisation procedure. A. laidlawii may flourish and survive for prolonged periods at refrigeration and ambient temperatures in serum-free cell culture media.