Harman Patil (Editor)

Acediasulfone

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Covid-19
ATC code  none
PubChem CID  66451
UNII  30YP2YHH8W
Molar mass  306.337 g/mol
CAS Number  80-03-5
ChemSpider  59823
ChEMBL  CHEMBL48396
Acediasulfone httpsuploadwikimediaorgwikipediacommonsthu

How to pronounce acediasulfone


Acediasulfone (INN) is an antimicrobial drug, which also has antimalarial activity. It is a long-acting prodrug of dapsone, which is used for treating leprosy.

Contents

Synthesis

Dapsone is somewhat inconvient to administer to patients because of its rather low water solubility.

In the search for more easily administered drugs, 1 was reacted with bromoacetic acid to give acediasulfone (3) which can be adminsistered as a water soluble salt.

References

Acediasulfone Wikipedia


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