ATC code none PubChem CID 66451 UNII 30YP2YHH8W Molar mass 306.337 g/mol | CAS Number 80-03-5 ChemSpider 59823 ChEMBL CHEMBL48396 | |
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How to pronounce acediasulfone
Acediasulfone (INN) is an antimicrobial drug, which also has antimalarial activity. It is a long-acting prodrug of dapsone, which is used for treating leprosy.
Contents
Synthesis
Dapsone is somewhat inconvient to administer to patients because of its rather low water solubility.
In the search for more easily administered drugs, 1 was reacted with bromoacetic acid to give acediasulfone (3) which can be adminsistered as a water soluble salt.
References
Acediasulfone Wikipedia(Text) CC BY-SA