Harman Patil (Editor)

Abafungin

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Trade names
  
Abasol

ATC code
  
none

PubChem CID
  
159326

Molar mass
  
378.491 g/mol

Routes of administration
  
Topical (cream)

CAS Number
  
129639-79-8

ChemSpider
  
140124

Abafungin wwwchemspidercomImagesHandlerashxid140124ampw

What does abafungin mean


Abafungin (INN) is a broad-spectrum antifungal agent with a novel mechanism of action for the treatment of dermatomycoses.

Contents

Abasol is a topical cream formulation of abafungin by York Pharma.

How to pronounce abafungin


Mechanism of action

Unlike imidazole- and triazole-class antifungals, abafungin directly impairs the fungal cell membrane.

In addition, abafungin inhibits the enzyme sterol 24-C-methyltransferase, modifying the composition of the fungal membrane.

Abafungin has antibiotic activity against gram-positive bacteria as well as sporicidal activity.

References

Abafungin Wikipedia