| AP4M1, CPSQ3, MU-4, MU-ARP2, SPG50, adaptor related protein complex 4 mu 1 subunit|
MGI: 1337063 HomoloGene: 3467 GeneCards: AP4M1
AP-4 complex subunit mu-1 is a protein that in humans is encoded by the AP4M1 gene.
This gene encodes a subunit of the heterotetrameric AP-4 complex. The encoded protein belongs to the adaptor complexes medium subunits family. This AP-4 complex is involved in the recognition and sorting of cargo proteins with tyrosine-based motifs from the trans-golgi network to the endosomal-lysosomal system.
AP4M1 has been shown to interact with AP4B1.
The AP4-complex-mediated trafficking plays a crucial role in brain development and functioning.