Harman Patil

AKAP3

Updated on
Share on FacebookTweet on TwitterShare on LinkedIn
Species  Human
Entrez  10566
Human  Mouse
Ensembl  ENSG00000111254
AKAP3
Aliases  AKAP3, AKAP 110, AKAP110, CT82, FSP95, HEL159, PRKA3, SOB1, A-kinase anchoring protein 3
External IDs  MGI: 1341149 HomoloGene: 4688 GeneCards: AKAP3

A-kinase anchor protein 3 is an enzyme that in humans is encoded by the AKAP3 gene.

Contents

Function

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family, and is expressed in testis only. The encoded protein contains an RII-binding domain, and is predicted to participate in protein-protein interactions with the R-subunit of the PKA. This protein is localized to the ribs of the fibrous sheath in the principal piece of the sperm tail. It may function as a regulator of both motility- and head-associated functions such as capacitation and the acrosome reaction.

Interactions

AKAP3 has been shown to interact with:

  • AKAP4
  • GNA13, and
  • PRKAR2A.
  • References

    AKAP3 Wikipedia


    Similar Topics
    Santos (DJ)
    Bernardim Ribeiro
    Topics