Species Human Entrez 3983 | Human Mouse Ensembl ENSG00000099204 | |
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Aliases ABLIM1, ABLIM, LIMAB1, LIMATIN, abLIM-1, actin binding LIM protein 1 External IDs MGI: 1194500 HomoloGene: 40994 GeneCards: ABLIM1 | ||
Actin binding LIM protein 1, also known as ABLIM1, is a protein which in humans is encoded by the ABLIM1 gene.
Contents
Function
This gene encodes a cytoskeletal LIM protein that binds to actin filaments via a domain that is homologous to erythrocyte dematin. LIM domains, found in over 60 proteins, play key roles in the regulation of developmental pathways. LIM domains also function as protein-binding interfaces, mediating specific protein-protein interactions. The protein encoded by this gene could mediate such interactions between actin filaments and cytoplasmic targets. Alternatively spliced transcript variants encoding different isoforms have been identified.
Interactions
ABLIM1 has been shown to interact with LDOC1.
References
ABLIM1 Wikipedia(Text) CC BY-SA