Puneet Varma (Editor)

4 HO DET

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CAS Number
  
22204-89-3

ChemSpider
  
8167136

Formula
  
C14H20N2O

PubChem CID
  
9991554

ChEMBL
  
CHEMBL143202

4-HO-DET

Legal status
  
DE: Anlage I (Controlled) UK: Class A

4-HO-DET, also known as 4-hydroxy-diethyl-tryptamine, CZ-74, or ethocin, is a hallucinogenic drug and psychedelic compound of moderate duration. 4-HO-DET is a substituted tryptamine, structurally related to psilocin and 4-HO-DIPT.

Contents

Analogs

The acetic acid ester of 4-HO-DET is known as 4-AcO-DET or ethacetin. The phosphoric acid ester of 4-HO-DET is known as 4-phosphoryloxy-DET, CEY-19, or ethocybin.

History

4-HO-DET received the lab code CZ-74 in the late 1950s by the inventors of the substance, Albert Hofmann and Franz Troxler. The substance was used together with its phosphoryloxy-analog CEY-19 in human clinical trials in the 1960s by the German researchers Hanscarl Leuner and G. Baer.

Dosage

10-25mg is the usual oral dosage for 4-HO-DET, while the acetate and phosphate esters are said to require a slightly higher dosage.

Effects

Ethocin produces entheogenic effects similar to LSD and psilocybin. Some users have reported unpleasant anxiety and stimulation with this drug, while other accounts label the experience as being much milder than LSD or psilocybin.

Sweden

Sveriges riksdags health ministry Statens folkhälsoinstitut classified 4-HO-DET as "health hazard" under the act Lagen om förbud mot vissa hälsofarliga varor (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-hydroxi-N,N-dietyltryptamin (4-HO-DET), making it illegal to sell or possess.

References

4-HO-DET Wikipedia