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A succession crisis erupts at Cunobelin's court and his exiled younger son Adminius flees to the court of Emperor Caligula in Rome.
40
Caligula plans an invasion of Britain but turns back before reaching the coast of Gaul.
42
Approximate date of the death of Cunobelin. His sons Caratacus and Togodumnus expand Catuvellauni territory into the Atrebates, driving out king Verica.
Verica travels to Rome to appeal to Emperor Claudius to help him regain his throne.
Roman conquest of Britain: General Vespasian captures the River Medway and forces Britons back across the Thames.
September - Roman conquest of Britain: Emperor Claudius brings reinforcements and captures Colchester; Britons including Caratacus and Togodumnus surrender.
Roman conquest of Britain: Aulus Plautius becomes first Governor of Roman Britain.
Roman allies the Iceni of East Anglia are ordered to surrender their weapons by new Roman Governor of Britain Ostorius Scapula. Some tribesmen resist and are quickly put down. Prasutagus takes over as king of the Iceni at about this time.
48
Romans defeat the Deceangli tribes of north-eastern Wales.
49
Silures tribes of southern Wales attack the Romans, but are held back by newly constructed forts.
Roman citizen-colony is founded at Camulodunum (Colchester).
51
Caratacus leads the Ordovices of north-western Wales against the Romans, but is defeated and captured.
Paulinus captures Anglesey, the last stronghold of the druids.
Prasutagus, king of the Iceni (in modern East Anglia), dies leaving a will which passes his kingdom to his two daughters and emperor Nero. The Roman army however annexes the kingdom as if conquered, depriving the nobles of their hereditary lands and plundering the land. The king's widow, Boudica, is flogged and forced to watch their daughters publicly raped. Roman financiers, including Seneca the Younger, call in their loans.
Paulinus defeats the rebels at the Battle of Watling Street using a flying wedge formation, and imposes wide-ranging punishments on native Britons, but is removed from office after an enquiry instituted by Gaius Julius Alpinus Classicianus (appointed procurator 61) and the Romanization of Britain continues. Boudica either poisons herself or falls sick and dies.