The 1921 All-Western college football team consists of American football players selected to the All-Western teams chosen by various selectors for the 1921 college football season.
Fritz Crisler, Chicago (COL-1, WE-1) (CFHOF)
Lester Belding, Iowa (COL-1, WE-2)
Truck Myers, Ohio State (WE-1)
Paul G. Goebel, Michigan (COL-2, WE-3)
Gus Tebell, Wisconsin (COL-2, WE-3)
Stevens Gould, Wisconsin (WE-2)
Duke Slater, Iowa (COL-1, WE-1) (CFHOF)
Charles McGuire, Chicago (COL-1, WE-1)
Iolas Huffman, Ohio State (COL-2, WE-2)
James Brader, Wisconsin (COL-2, WE-2)
Robert H. Spiers, Ohio State (WE-3)
Ed Carman, Purdue (WE-3)
Dean W. Trott, Ohio State (COL-1, WE-1)
Lloyd Pixley, Ohio State (COL-1)
Robert J. Dunne, Michigan (WE-1)
Charles Redmon, Chicago (COL-2, WE-2)
Ferdinand Birk, Purdue (COL-2)
Albert W. T. Mohr, Jr., Illinois (WE-2)
Paul Minick, Iowa (WE-3)
William G. McCaw, Indiana (WE-3)
George C. Bunge, Wisconsin (COL-1, WE-2)
Ernie Vick, Michigan (COL-2, WE-1) (CFHOF)
Jack Heldt, Iowa (WE-3)
Aubrey Devine, Iowa (COL-1, WE-1) (CFHOF)
Hoge Workman, Ohio State (COL-2)
Milton Romney, Chicago (WE-2)
Irwin Uteritz, Michigan (WE-3)
Alvah Elliott, Wisconsin (COL-1, WE-1)
Roland Williams, Wisconsin (COL-1)
Don Peden, Illinois (WE-1)
John D. Stuart, Ohio State (COL-2, WE-3)
Stevens Gould, Wisconsin (COL-2)
Franklin Cappon, Michigan (WE-2)
Laurie Walquist, Illinois (WE-2)
Earl Martineau, Minnesota (WE-3)
Gordon Locke, Iowa (COL-1, WE-1) (CFHOF)
Guy Sundt, Wisconsin (COL-2, WE-3)
Thomas, Chicago (WE-2)
COL = Collier's Weekly selected by E. C. Patterson and Billy Evans
WE = Walter Eckersall in the Chicago Tribune (all-conference)
CFHOF = College Football Hall of Fame