The 1921 All-Big Ten Conference football team consists of American football players selected to the All-Big Ten Conference teams chosen by various selectors for the 1921 Big Ten Conference football season.
Fritz Crisler, Chicago (BE-1; CA-1; WE-1; LH-1)
Stevens Gould, Wisconsin (CA-1; WE-1; LH-1; BE-2 [halfback])
Truck Myers, Ohio State (WE-1; LH-1)
Lester Belding, Iowa (BE-1; WE-2)
Gus Tebell, Wisconsin (BE-2; WE-3)
Paul G. Goebel, Michigan (BE-2; WE-3)
Charles McGuire, Chicago (BE-1; CA-1; WE-1; LH-1)
Duke Slater, Iowa (BE-1; CA-1; WE-1; LH-1)
James Brader, Wisconsin (BE-2; WE-2)
Iolas Huffman (BE-2; WE-2)
Robert H. Spiers, Ohio State (WE-3)
Ed Carman, Purdue (WE-3)
Robert J. Dunne, Michigan (CA-1; WE-1; LH-1)
Lloyd Pixley, Ohio State (BE-1; CA-1; LH-1)
Dean W. Trott, Ohio State (BE-1; WE-1)
Charles Redmon, Chicago (BE-2; WE-2)
Albert W. T. Mohr, Jr., Illinois (WE-2)
Ferdinand Birk, Purdue (BE-2)
Paul Minick, Iowa (WE-3)
William G. McCaw, Indiana (WE-3)
Ernie Vick, Michigan (BE-2; CA-1; WE-1)
George C. Bunge, Wisconsin (BE-1; WE-2; LH-1)
Jack Heldt, Iowa (WE-3)
Aubrey Devine, Iowa (BE-1; CA-1; WE-1; LH-1)
Milton Romney, Chicago (CA-2; WE-2)
Hoge Workman, Ohio State (BE-2)
Irwin Uteritz, Michigan (WE-3)
Alvah Elliott, Wisconsin (BE-1; CA-1; WE-1; LH-1)
Laurie Walquist, Illinois (CA-2; WE-2; LH-1)
John D. Stuart, Ohio State (BE-2; CA-1; WE-3)
Don Peden, Illinois (WE-1)
Roland Williams, Wisconsin (BE-1)
Franklin Cappon, Michigan (CA-2; WE-2)
Earl Martineau, Minnesota (WE-3)
Gordon Locke, Iowa (BE-1; CA-1; WE-1; LH-1)
Guy Sundt, Wisconsin (BE-2; CA-2; WE-3)
John Webster Thomas, Chicago (WE-2)
BE = Billy Evans, "N.E.A. Sports Expert; American League Umpire; and Football Official"
CA = Chicago American, selected by Harold Johnson
WE = Walter Eckersall for the Chicago Tribune
LH = Luther A. Huston of the International News Service