Year 1469 (MCDLXIX) was a common year starting on Sunday (link will display the full calendar) of the Julian calendar.
October 19 – Ferdinand II of Aragon marries Isabella I of Castile in Valladolid, bringing about a dynastic union of Spain.
Sigismund of Austria sells Upper-Elsass (Alsace) to Charles the Bold in exchange for aid in a war against the Swiss.
Moctezuma I, Aztec ruler of Tenochtitlan, dies and is succeeded by Axayacatl.
Marsilio Ficino completes his translation of the collected works of Plato, writes "Commentary on Plato's Symposium on Love" and starts to work on "Platonic Theology".
February 13 – Elia Levita, Renaissance Hebrew grammarian (d. 1549)
February 20 – Thomas Cajetan, Italian philosopher (d. 1534)
March 20 – Cecily of York, English princess (d. 1507)
April 15 – Guru Nanak, Sikh guru (d. 1539)
April 29 – William II, Landgrave of Hesse (d. 1509)
May 3 – Niccolò Machiavelli, Italian historian and political author (d. 1527)
May 31 – King Manuel I of Portugal (d. 1521)
June 20 – Gian Galeazzo Sforza, Duke of Milan (d. 1494)
August 4 – Margaret of Saxony, Duchess of Brunswick-Lüneburg (d. 1528)
August 26 – King Ferdinand II of Naples (d. 1496)
date unknown
John III of Navarre (d. 1516)
Silvio Passerini, Italian politician (d. 1529)
Laura Cereta, Italian humanist and feminist (d. 1499)
probable – Vasco da Gama, explorer (d. 1524)
May 30 – Lope de Barrientos, a powerful bishop in Castile (b. 1389)
August 12 – Richard Woodville, 1st Earl Rivers (executed) (b. 1412)
October 8 – Filippo Lippi, artist (b. 1406)
December 2 – Piero di Cosimo de' Medici, ruler of Florence (b. 1416)
date unknown
Abu Sa'id, ruler of Persia and Afghanistan (b. 1424)
Lope de Barrientos, powerful Castilian cleric (b. 1382)
Niccolò Da Conti, Italian merchant and explorer (b. 1395)
Andrew Gray, 1st Lord Gray (b. approx. 1390)
Moctezuma I, Aztec ruler of Tenochtitlan
1469 Wikipedia (Text) CC BY-SA