|EC number 126.96.36.199|
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|CAS number 103537-12-8|
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KEGG KEGG entry
In enzymology, a [tyrosine 3-monooxygenase] kinase (EC 188.8.131.52) is an enzyme that catalyzes the chemical reactionATP + [tyrosine-3-monooxygenase]
Thus, the two substrates of this enzyme are ATP and tyrosine 3-monooxygenase, whereas its two products are ADP and [[phospho-[tyrosine-3-monooxygenase]]].
This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[tyrosine-3-monoxygenase] phosphotransferase. Other names in common use include pheochromocytoma tyrosine hydroxylase-associated kinase, STK4, and tyrosine 3-monooxygenase kinase (phosphorylating). This enzyme participates in MAPK signaling pathway and non-small cell lung cancer.