Kalpana Kalpana (Editor)

(tyrosine 3 monooxygenase) kinase

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EC number
IntEnz  IntEnz view
ExPASy  NiceZyme view
CAS number  103537-12-8
KEGG  KEGG entry

In enzymology, a [tyrosine 3-monooxygenase] kinase (EC is an enzyme that catalyzes the chemical reaction

ATP + [tyrosine-3-monooxygenase] ADP + phospho-[tyrosine-3-monooxygenase]

Thus, the two substrates of this enzyme are ATP and tyrosine 3-monooxygenase, whereas its two products are ADP and [[phospho-[tyrosine-3-monooxygenase]]].

This enzyme belongs to the family of transferases, specifically those transferring a phosphate group to the sidechain oxygen atom of serine or threonine residues in proteins (protein-serine/threonine kinases). The systematic name of this enzyme class is ATP:[tyrosine-3-monoxygenase] phosphotransferase. Other names in common use include pheochromocytoma tyrosine hydroxylase-associated kinase, STK4, and tyrosine 3-monooxygenase kinase (phosphorylating). This enzyme participates in MAPK signaling pathway and non-small cell lung cancer.


(tyrosine 3-monooxygenase) kinase Wikipedia