Yarborough is a surname. Notable people with the surname include:
Charles Anderson-Pelham, 2nd Earl of Yarborough, after whom the bridge hand is named
A yarborough is an especially weak hand in contract bridge
Cale Yarborough, retired NASCAR driver and three time Winston Cup Champion
Emmanuel Yarborough, American Sumo wrestler
Ralph Yarborough (1903–96), Texan politician
William P. Yarborough, Brigadier General during the Kennedy administration
