PubChem CID 5281575 | ||
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Yangonin puisto 2016
Yangonin is one of the six major kavalactones found in the kava plant. It has been shown to possess binding affinity for the cannabinoid receptor CB1 (Ki = 0.72 μM), where it behaves as an agonist.
Contents
Yangonin el m
Toxicity
Yangonin displays marked in vitro toxicity on human hepatocytes with approximately 40% reduction in viability based on an ethidium bromide assay. The predominant mode of cell death turned out to be apoptosis rather than necrosis. No significant changes were observed in glutathione levels.
References
Yangonin Wikipedia(Text) CC BY-SA