Species Human Entrez 10971 | Human Mouse Ensembl ENSG00000134308 | |
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Aliases YWHAQ, 14-3-3, 1C5, HS1, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta External IDs MGI: 3650241 HomoloGene: 105677 GeneCards: YWHAQ | ||
Gene music using protein sequence of ywhaq tyrosine 3 monooxygenase tryptophan 5 monooxygenase act
14-3-3 protein theta is a protein that in humans is encoded by the YWHAQ gene.
Contents
Function
This gene product belongs to the 14-3-3 family of proteins that mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse and rat orthologs. This gene is upregulated in patients with amyotrophic lateral sclerosis. It contains in its 5' UTR a 6 bp tandem repeat sequence that is polymorphic; however, there is no correlation between the repeat number and the disease.
Interactions
YWHAQ has been shown to interact with:
References
YWHAQ Wikipedia(Text) CC BY-SA