Samiksha Jaiswal (Editor)

YWHAG

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Species
  
Entrez
  
7532

Human
  
Ensembl
  
ENSG00000170027

YWHAG

Aliases
  
YWHAG, 14-3-3GAMMA, PPP1R170, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma

External IDs
  
MGI: 108109 HomoloGene: 22725 GeneCards: YWHAG

14-3-3 protein gamma is a protein that in humans is encoded by the YWHAG gene.

This gene product belongs to the 14-3-3 protein family which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

Interactions

YWHAG has been shown to interact with C-Raf, EPB41L3, KIF1C and Stratifin.

References

YWHAG Wikipedia


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