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Werner and Gertrude Henle

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Name  Werner Gertrude

Werner and Gertrude Henle wwwupennedualmanacvolumesv53n04imagesn04G

Werner Henle (August 27, 1910 – July 6, 1987) and Gertrude Henle (April 3, 1912 – September 1, 2006) were a husband and wife team of virologists known for their work in flu vaccines and viral diagnostics. Together they authored more than 200 papers.


Gertrude Henle

Gertrude Henle , born Szpingier, on April 3, 1912 in Mannheim, Germany. She died age 94 on September 1, 2006 in Newtown Square , Pennsylvania. She was an American virologist.

Henle came from a Protestant family of civil servants and grew up in Mannheim. Her mother was murdered by the Nazis in 1943, her father died in 1938. Henle studied from 1931 medicine at the University of Heidelberg, and earned her medical degree in 1936.

For her doctorate, she was at the Kaiser Wilhelm Institute for Medical Research, where she met her husband Werner Henle, whom she followed to Philadelphia in 1937, in the U.S., where they married in 1937. Both worked in their careers closely related. She was from 1937 Instructor of Microbiology at the University of Pennsylvania , 1941 Associate Professor of Virology (and member of the Research Department of Virology at the Children's Hospital of Philadelphia). Later she became a professor. In 1982, she retired, the same year as her husband. Gertrude and Werner Henle are known for their work on flu vaccination and the development of a test for mumps known. They also reported the carcinogenic effects of the Epstein-Barr virus after and investigated further tumor viruses . They showed the effect of gamma with Joseph Stokes globulin against hepatitis . She has published mostly with her husband over 200 scientific papers. In the 1980s they worked with AIDS.

In 1975 she was made an honorary Doctor of Pennsylvania College of Medicine. She was a U.S. citizen since 1942.

Werner Henle

Werner Henle was born August 27, 1910 in Dortmund, Germany and died July 6, 1987 in Bryn Mawr , Pennsylvania. He was a German-American virologist .

Henle was the son of a surgeon Adolf Henle and the grandson of Jacob Henle . He studied medicine and received his doctorate in Heidelberg. There he met his wife Gertrude Szpingier , also a graduate student physician. Both emigrated to the USA in 1936 and married in 1937. The marriage remained childless. Henle was in 1936 at the University of Pennsylvania and from 1939 at the same time at the Children's Hospital of Philadelphia worked. Together with his wife could Henle made some fundamental discoveries in the field of virus diagnostics. Together with Dr. Joseph Stokes Jr. they showed the efficacy of gamma globulin against hepatitis infections. Finally, they worked successfully in the field of rapid diagnostics for mumps.

In the years 1962/1963 Werner Henle served as president of the American Association of Immunologists .


In 1968, they discovered how to immunize against the Epstein–Barr virus and confirmed a link between this virus and infectious mononucleosis.


  • The Gold Medal of the Children's Hospital of Philadelphia (1983)
  • Bristol-Myers Award (1979)
  • William B. Coley Award (1975)
  • the Virus Cancer Program Award (1975)
  • Robert Koch Prize (1971)
  • E. Mead Johnson Award (1950)
  • References

    Werner and Gertrude Henle Wikipedia

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