Nationality Swiss Name Walter Gehring | Fields Developmental biology | |
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Born 20 March 1939Zurich, Switzerland ( 1939-03-20 ) Institutions University of Zurich, Yale Medical School, Yale University, Biozentrum University of Basel Died May 29, 2014, Basel, Switzerland Books Master control genes in development and evolution, The Harvey Lecture Awards Gairdner Foundation International Award Similar People Rudiger Wehner, Eric F Wieschaus, Christiane Nusslein‑Volhard, Edward B Lewis, Alexander F Schier | ||
Walter Jakob Gehring (1939 – 29 May 2014) was a Swiss developmental biologist who was a professor at the Biozentrum Basel of the University of Basel, Switzerland. He obtained his PhD at the University of Zurich in 1965 and after two years as a research assistant of Professor Ernst Hadorn he joined Professor Alan Garen's group at Yale University in New Haven as a postdoctoral fellow.
In 1969 he was appointed as an associate professor at the Yale Medical School and 1972 he returned to Switzerland to become a professor of developmental biology and genetics at the Biozentrum of the University of Basel. He was Secretary General of the European Molecular Biology Organization, President of the International Society of Developmental Biologists, a Foreign Member of the National Academy of the USA, Great Britain, France, Germany and Sweden.
Walter Gehring has mainly been involved in studies of Drosophila genetics and development, particularly in the analysis of cell determination in the embryo and transdetermination of imaginal discs. He has made significant contributions to the study of the heat shock genes, various transposons and the homeotic genes which are involved in the genetic control of development.
In 1983 Gehring and his collaborators (William McGinnis, Michael S. Levine, Ernst Hafen, Richard Garber, Atsushi Kuroiwa, Johannes Wirz), discovered the homeobox, a DNA segment characteristic for homeotic genes which is not only present in arthropods and their ancestors, but also in vertebrates including man.
Gehring has also been involved in the development and application of enhancer trapping methods. He and his collaborators have identified PAX6 as a master control gene for eye development, which led to a new theory about the monophyletic origin of the eyes in evolution.