Samiksha Jaiswal (Editor)

WY 46824

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Formula
  
C19H29ClN2O

Molar mass
  
336.8994 g/mol

ChEMBL ID
  
511347

3D model (Jmol)
  
Interactive image

PubChem CID
  
10314993

ChemSpider ID
  
8490458

WY-46824 httpsuploadwikimediaorgwikipediacommonsthu

WY-46824 is a norepinephrine-dopamine reuptake inhibitor that was disclosed by Paige Mahaney, et al. of Wyeth in 2008. The compound actually appears in an article a year earlier in 2007 but is not the main focus of the work. These are the only two citations that can be found for it on PubMed. It has been patented but presumably within the framework of it being an analog of venlafaxine.

It has NET binding of 46 nM, DAT = 58 nM and SERT = 18795 nM. The racemic compound was resolved into its constituent enantiomers.

References

WY-46824 Wikipedia