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Vonoprazan

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Trade names
  
Takecab

Bioavailability
  
Unknown

Biological half-life
  
7.7 h

ChemSpider ID
  
13112797

Excretion
  
Renal

ATC code
  
None

Protein binding
  
80%

Molar mass
  
461.46 g/mol

Trade name
  
Takecab

Vonoprazan fileselleckchemcomdownloadsstructTAK438chem

Metabolism
  
Hepatic, by cytochrome P450 (3A4, 2B6, 2C19, 2D6)

Vonoprazan fumarate is a first-in-class potassium-competitive acid blocker. It was approved in the Japanese market in February 2015.

Vonoprazan can be used for the treatment of gastroduodenal ulcer (including some drug-induced peptic ulcers) and reflux esophagitis, and can be combined with antibiotics for the eradication of Helicobacter pylori.

References

Vonoprazan Wikipedia