EC number 3.6.3.33 | ExPASy NiceZyme view MetaCyc | |
In enzymology, a vitamin B12-transporting ATPase (EC 3.6.3.33) is an enzyme that catalyzes the chemical reaction
ATP + H2O + vitamin B12out
The 3 substrates of this enzyme are ATP, H2O, and vitamin B12, whereas its 3 products are ADP, phosphate, and vitamin B12.
This enzyme belongs to the family of hydrolases, specifically those acting on acid anhydrides to catalyse transmembrane movement of substances. The systematic name of this enzyme class is ATP phosphohydrolase (vitamin B12-importing). This enzyme participates in abc transporters - general.
Structural studies
As of late 2007, two structures have been solved for this class of enzymes, with PDB accession codes 1L7V and 2QI9.
References
Vitamin B12-transporting ATPase Wikipedia(Text) CC BY-SA