van Niekerk is a common Afrikaans surname. Notable people with the surname include:
Barend van Niekerk (1939–1981), South African lawyer and academic
Dane van Niekerk (born 1993), South African cricketer
Helga van Niekerk, South African radio personality
Janro van Niekerk (born 1982), South African rugby union player
Joe van Niekerk (born 1980), South African rugby union player
Kraai van Niekerk (born 1938), South African politician
Marlene van Niekerk (born 1954), South African writer
Martin van Niekerk (born 1989), Namibian cricketer
Wayde van Niekerk (born 1992), South African sprinter
