Vaccaro is a surname. Notable people with the surname include:
Adolfo Vaccaro (b. 1927), Paraguayan football player and coach
Alessandra Melucco Vaccaro (1940–2000), Italian historian and archaeologist
Andrea Vaccaro (1600–1670), Neapolitan painter of the Baroque period
Angelo Vaccaro (b. 1981), Italian football player
Brenda Vaccaro (b. 1939), American actress
Cris Vaccaro (b. 1958), American professional soccer player
Domenico Antonio Vaccaro (1678–1745), Neapolitan painter, sculptor and architect
Francesco Vaccaro (c. 1636–1675), Bolognese painter and engraver of the Baroque period
Joan Vaccaro, physicist at Griffith University
Kenny Vaccaro, professional gridirion player
Laura Vaccaro Seeger, American children's books author and artist
Leopold Saverio Vaccaro, reconstruction figure in post-World War I Italy
Lorenzo Vaccaro (1655–1706), Neapolitan late-Baroque sculptor
Luigi Vaccaro (b. 1991), Belgian football player
Mike Vaccaro, sports columnist for The New York Post
Sonny Vaccaro (b. 1939), American sports marketing executive
Tony Vaccaro (b. 1922), American photographer
Tracy Vaccaro (b. 1962), American model and actress
Vaccaro Brothers, Honduran banana businessmen
