Entrez 57617 | Ensembl ENSG00000104142 | |
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Aliases VPS18, PEP3, CORVET/HOPS core subunit External IDs MGI: 2443626 HomoloGene: 13302 GeneCards: VPS18 | ||
Vacuolar protein sorting-associated protein 18 homolog is a protein that in humans is encoded by the VPS18 gene.
Contents
Function
Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human homolog of yeast class C Vps18 protein. The mammalian class C Vps proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway.
Interactions
References
VPS18 Wikipedia(Text) CC BY-SA