Samiksha Jaiswal (Editor)

Urofollitropin

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Trade names
  
Bravelle, Fertinex

CAS Number
  
146479-72-3

CAS ID
  
146479-72-3

Trade name
  
Bravelle, Fertinex

Legal status
  
US: ℞-only

Molar mass
  
22,672.9 g/mol

ATC code
  
G03GA04 (WHO)

Formula
  
C975H1513N267O304S26

AHFS/Drugs.com
  
Micromedex Detailed Consumer Information

Pregnancy category
  
US: X (Contraindicated)

Routes of administration
  
Subcutaneous, intramuscular

Fertility treatment follistim aq cartridge with follistim pen


Urofollitropin is a purified form of follicle-stimulating hormone (FSH) that is manufactured by extraction from human urine and then purified to remove various proteins and other substances. FSH is important in the development of follicles (eggs) produced by the ovaries. Given by subcutaneous injection, it is used in combination with human chorionic gonadotropin (hCG) to assist in ovulation and fertility. It is also used with in vitro fertilization methods. The dosage is adjusted to each individual's response.

The most common side effects are abdominal or pelvic pain, bloating, as well as redness, pain or swelling at the injection site. Follitropin is possibly associated with increased risk of endometrial carcinoma. It is not for use during pregnancy, as there is evidence for birth defects under follitropin treatment.

Bravelle sold in the United States from March 2014 through October 2015 is subject to a recall and refund by its maker, Ferring Pharmaceuticals, because certain batches of the medicine had a lower strength than stated.

References

Urofollitropin Wikipedia