EC number 3.5.3.19 IntEnz IntEnz view ExPASy NiceZyme view | CAS number 115629-07-7 BRENDA BRENDA entry KEGG KEGG entry | |
In enzymology, an ureidoglycolate hydrolase (EC 3.5.3.19) is an enzyme that catalyzes the chemical reaction
(S)-ureidoglycolate + H2OThus, the two substrates of this enzyme are (S)-ureidoglycolate and H2O, whereas its 3 products are glyoxylate, NH3, and CO2.
This enzyme belongs to the family of hydrolases, those acting on carbon-nitrogen bonds other than peptide bonds, specifically in linear amidines. The systematic name of this enzyme class is (S)-ureidoglycolate amidohydrolase (decarboxylating). This enzyme participates in purine metabolism.
Structural studies
As of late 2007, 4 structures have been solved for this class of enzymes, with PDB accession codes 1XSQ, 1XSR, 1YQC, and 2BDR.
References
Ureidoglycolate hydrolase Wikipedia(Text) CC BY-SA