Puneet Varma (Editor)

Urea containing cream

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Routes ofadministration
  
Topical

Legal status
  
US: OTC

ATC code
  
D02AE01 (WHO)


Trade names
  
Decubal, Carmol 40, Keralac, others

AHFS/Drugs.com
  
Multum Consumer Information

Pregnancycategory
  
US: C (Risk not ruled out)

Urea, also known as carbamide-containing cream, is used as a medication and applied to the skin to treat dryness and itching such as may occur in psoriasis, dermatitis, or ichthyosis. It may also be used to soften nails.

Contents

In adults side effects are generally few. It may occasionally cause skin irritation. Urea works in part by loosening dried skin. Preparations generally contain 5 to 50% urea.

Urea containing creams have been used since the 1940s. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. It is avaliable over the counter. In the United Kingdom 100 g of 10% cream costs the NHS about 4.37 pounds.

Urea-containing cream Urea Cream FDA prescribing information side effects and uses

Medical uses

Urea-containing cream Urea Cream on Pharmacy Online

Urea cream is indicated for debridement and promotion of normal healing of skin areas with hyperkeratosis, particularly where healing is inhibited by local skin infection, skin necrosis, fibrinous or itching debris or eschar. Specific condition with hyperkeratosis where urea cream is useful include:

  • Dry skin and rough skin
  • Dermatitis
  • Psoriasis
  • Ichthyosis
  • Eczema
  • Keratosis
  • Keratoderma
  • Corns
  • Calluses
  • Damaged, ingrown and devitalized nails
  • Side effects

    More common side effects of urea cream are:

  • Mild skin irritation
  • Temporary burning sensation
  • Stinging sensation
  • Itching

  • Urea-containing cream Urea Ointment FDA prescribing information side effects and uses

    In severe cases, there can be an allergic reaction with symptoms such as skin rash, urticaria, difficulty breathing and swelling of the mouth, face, lips, or tongue.

    Mechanism of action

    Urea-containing cream Urea Cream Exfoliating Cream Foot Cream Dry Feet Cream Kera 42

    Urea dissolves the intercellular matrix of the cells of the stratum corneum, promoting desquamation of scaly skin, eventually resulting in softening of hyperkeratotic areas. In nails, urea causes softening and eventually debridement of the nail plate.

    Urea-containing cream Urea Cream on Pharmacy Online

    Urea-containing cream Amazoncom Topix Urix 40 Urea Cream 8oz Body Lotions Beauty

    References

    Urea-containing cream Wikipedia


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