Baron Osvaldo Lambertenghi is forced to sell his ancestral castle for debts. The manor is ingloriously transformed into a frivolous hotel and Osvaldo is allowed to continue to live there working as a porter. One day Osvaldo receives a visit from his uncle Roderico, who turns out to be a real vampire. Osvaldo tries to warn of what the various guests of the hotel, with the only result of being taken for a madman. Bitten by his uncle, Oswald will also turn into a vampire, but his beloved Lellina will be able to free him from the curse.
Renato Rascel: Baron Osvaldo Lambertenghi
Christopher Lee: Baron Roderico da Frankurten
Sylva Koscina: Carla
Kai Fischer: Lellina
Lia Zoppelli: Letizia
Franco Scandurra: Professor Stricker
Carl Wery: Director
Rik Van Nutter: Fianceè of Carla
Susanne Loret: Susan
Mario Cecchi Gori: Civil-law notary
Uncle Was a Vampire was Christopher Lee's first entry into an Italian film production.
Bruno Martino's song "Dracula cha-cha" is played over the credits of the film.
Uncle Was a Vampire was released in Italy on October 28, 1959 where it was distributed by C.E.I.-Incom. It grossed a total of 385 million lire in Italy. The film was Italy first vampire film. The film was released in the USA in 1964 on television through Embassy Pictures Television
In his book Italian Horror Film Directors, Louis Paul described the film as "obviously modeled on the slapstick efforts of the comedies featuring the character Toto".