Girish Mahajan (Editor)

UQCRFS1

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Species
  
Human

Entrez
  
7386

Human
  
Mouse

Ensembl
  
ENSG00000169021

UQCRFS1

Aliases
  
UQCRFS1, RIP1, RIS1, RISP, UQCR5, ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1

External IDs
  
MGI: 1913944 HomoloGene: 4378 GeneCards: UQCRFS1

Ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1, also known as UQCRFS1, is a protein which in humans is encoded by the UQCRFS1 gene.

UQCRFS1 is a subunit of the respiratory chain protein Ubiquinol Cytochrome c Reductase (UQCR, Complex III or Cytochrome bc1 complex), which consists of the products of one mitochondrially encoded gene:

  • MTCYTB (mitochondrial cytochrome b)

    • and ten nuclear genes:

  • UQCRC1, UQCRC2, Cytochrome C1, UQCRFS1 (this protein, a type of Rieske protein), UQCRB,UQCRQ ("11kDa protein"), UQCRH (cyt c1 Hinge protein), UCRC ("cyt. c1 associated protein"), and UQCR ("Rieske-associated protein").

    • After processing the cleaved leader sequence of the iron-sulfur protein is retained as subunit 9, giving 11 subunits from 10 genes.

    References

    UQCRFS1 Wikipedia
    (Text) CC BY-SA