Entrez 7336 | Ensembl ENSG00000169139 | |
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Aliases UBE2V2, DDVIT1, DDVit-1, EDAF-1, EDPF-1, EDPF1, MMS2, UEV-2, UEV2, ubiquitin conjugating enzyme E2 V2 External IDs MGI: 1917870 HomoloGene: 55739 GeneCards: UBE2V2 | ||
Ubiquitin-conjugating enzyme E2 variant 2 is a protein that in humans is encoded by the UBE2V2 gene.
Contents
Function
Ubiquitin-conjugating enzyme E2 variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein encoded by this gene also shares homology with ubiquitin-conjugating enzyme E2 variant 1 and yeast MMS2 gene product. It may be involved in the differentiation of monocytes and enterocytes.
Interactions
UBE2V2 has been shown to interact with HLTF.
References
UBE2V2 Wikipedia(Text) CC BY-SA