Entrez 7334 | Ensembl ENSG00000177889 | |
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Aliases UBE2N, HEL-S-71, UBC13, UBCHBEN; UBC13, UbcH-ben, UbcH13, ubiquitin conjugating enzyme E2 N External IDs MGI: 1934835 HomoloGene: 128406 GeneCards: UBE2N | ||
Function
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair.
Interactions
UBE2N has been shown to interact with:
References
UBE2N Wikipedia(Text) CC BY-SA