Tropane alkaloids are a class of bicyclic [3.2.1] alkaloids and secondary metabolites that contain a tropane ring in their chemical structure. Tropane alkaloids occur naturally in many members of the plant family Solanaceae. Some tropane alkaloids have pharmacological properties and can act as anticholinergics or stimulants.
Anticholinergic drugs and deliriants:Atropine, racemic hyoscyamine, from the deadly nightshade (Atropa belladonna)
Hyoscyamine, the levo-isomer of atropine, from henbane (Hyoscyamus niger) and mandrake (Mandragora officinarum)
Scopolamine, from henbane and Datura species (Jimson weed)
All three acetylcholine-inhibiting chemicals can also be found in the leaves, stems, and flowers in varying, unknown amounts in Brugmansia (angel trumpets), a relative of Datura.
Stimulants and cocaine-related alkaloids:Cocaine, from Erythroxylum coca
Ecgonine, a precursor and metabolite of cocaine
Benzoylecgonine, a metabolite of cocaine
Hydroxytropacocaine, from Erythroxylum coca
Methylecgonine cinnamate, from Erythroxylum coca
Catuabines, found in catuaba, an infusion or dry extract made from Erythroxylum vacciniifolium
There exist some synthetic analogs of tropane alkaloids, seePhenyltropanes
They are not considered to be alkaloids per definition.
Tropane alkaloid Wikipedia