Trisha Shetty (Editor)

Trimix (drug)

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Alprostadil
  
prostaglandin

Phentolamine
  
alpha blocker

Papaverine
  
vasodilator

Legal status
  
US: ℞-only

Pregnancy category
  
US: D (Evidence of risk)

Routes of administration
  
gel, injection, topical

Trimix is an injectable three-drug prescribed medication used to treat erectile dysfunction. The active ingredients in the mixture are usually alprostadil, papaverine, and phentolamine. The injection must be compounded by a pharmacy and administered via intracavernosal injection (an injection at the base of the penis). Trimix is typically compounded by a pharmacy in a sterile environment and then frozen. The compound is stable for up to 6 months while stored frozen and for 1 month if stored refrigerated beginning at the time of manufacture.

Dosage

The common initial dose should be .05cc to .2cc depending on the patients level of ED. Wait 48 hours before increasing dosage. Increase by 0.025 cc to 0.050 cc until a satisfactory dose is reached, or sometime it may subject to change by the doctor and or pharmacy. Its a strict prescribed medicine, due to the varying amount of dose, Purchasing/selling without prescription is illegal.

References

Trimix (drug) Wikipedia