Abbreviations TBSnA Boiling point 120 °C | Density 1.21 g/cm³ Chemical formula C12H27N3Sn Flash point > 110 °C (230 °F; 383 K) | |
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Appearance Colorless to light yellow liquid or white solid | ||
Tributyltin azide is an organotin compound. It is usually synthesized from tributyltin chloride and sodium azide.
Contents
Uses
Tributyltin azide is a reagent used in the synthesis of tetrazolylbenzene compounds. It has been used in pharmaceutical research and production to synthesize tetrazole derivatives, which in turn are used to create angiotensin II receptor antagonists.
In the above synthesis of tetrazole derivatives, tributyltin azide has been replaced by the less toxic trioctyltin azide and organoaluminium azides.
Safety
Lower alkyl tin compounds are generally highly toxic. Tributyltin azide has a penetrating odor, which is readily absorbed by other materials, for example, clothes of workers, reaction vessels or drying machines. Once the vapor is absorbed it is hard to remove. Skin exposure to tributyltin azide causes skin rashes, itching or blisters.