Symbol DP InterPro IPR014889 MEROPS S9 | Pfam PF08781 PROSITE PDOC00359 SCOP 1c5e | |
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In molecular biology, transcription factor DP (Dimerization Partner) is a family of proteins which function as transcription factors. DP forms a heterodimer with E2F and regulates genes involved in cell cycle progression. The transcriptional activity of E2F is inhibited by the retinoblastoma protein which binds to the E2F-DP heterodimer and negatively regulates the G1-S transition.
References
Transcription factor DP Wikipedia(Text) CC BY-SA