Entrez 10915 | Ensembl ENSG00000113649 | |
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Aliases TCERG1, CA150, TAF2S, Urn1, transcription elongation regulator 1 External IDs MGI: 1926421 HomoloGene: 4879 GeneCards: TCERG1 | ||
Transcription elongation regulator 1, also known as TCERG1, is a protein which in humans is encoded by the TCERG1 gene.
Contents
Function
This gene encodes a nuclear protein that regulates transcriptional elongation and pre-mRNA splicing. The encoded protein interacts with the hyperphosphorylated C-terminal domain of RNA polymerase II via multiple FF domains, and with the pre-mRNA splicing factor SF1 via a WW domain. Alternative splicing results in multiple transcripts variants encoding different isoforms.
Interactions
Transcription elongation regulator 1 has been shown to interact with SF1 and POLR2A.
References
Transcription elongation regulator 1 Wikipedia(Text) CC BY-SA