ATC code A10XA01 (WHO) CAS Number 82964-04-3 IUPHAR/BPS 7404 Molar mass 357.34 g/mol ChEMBL ID 436 IUPHAR/BP 7404 | Legal status Withdrawn from market PubChem CID 53359 UNII 0T93LG5NMK Pubchem 53359 ChemSpider ID 48194 | |
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What does tolrestat mean
Tolrestat (INN) (AY-27773) is an aldose reductase inhibitor which was approved for the control of certain diabetic complications.
Contents
While it was approved for marketed in several countries, it failed a Phase III trial in the U.S. due to toxicity and never received FDA approval. It was discontinued by Wyeth in 1997 because of the risk of severe liver toxicity and death. It was sold under the tradename Alredase.
How to pronounce tolrestat
References
Tolrestat Wikipedia(Text) CC BY-SA