AHFS/Drugs.com Monograph Routes of
administration Oral Molar mass 247.273 g/mol | MedlinePlus a604036 CAS ID 19387-91-8 Protein binding 12% | |
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Trade names Fasigyn, Simplotan, Tindamax Pregnancy
category AU: B3
US: C (Risk not ruled out) ATC code J01XD02 (WHO) P01AB02 (WHO) QP51AA02 (WHO) Trade name Fasigyn, Simplotan, Tindamax | ||
Tinidazole is an anti-parasitic drug used against protozoan infections. It is widely known throughout Europe and the developing world as a treatment for a variety of amoebic and parasitic infections. It was developed in 1972. A derivative of 2-methylimidazole, it is a prominent member of the nitroimidazole antibiotics.
Contents
Tinidazole is marketed by Mission Pharmacal under the brand name Tindamax, by Pfizer under the names Fasigyn and Simplotan, and in some Asian countries as Sporinex.
What does tinidazole mean
Uses
A large body of clinical data exists to support use of tinidazole for infections from amoebae, giardia, and trichomonas, just like metronidazole. Tinidazole may be a therapeutic alternative in the setting of metronidazole tolerance. Tinidazole may also be used to treat a variety of other bacterial infections (e.g., as part of combination therapy for Helicobacter pylori eradication protocols).
Side effects
Drinking alcohol while taking tinidazole causes an unpleasant disulfiram-like reaction, which includes nausea, vomiting, headache, increased blood pressure, flushing, and shortness of breath.
Half-life
Elimination half-life is 13.2 ± 1.4 hours. Plasma half-life is 12 to 14 hours.