Thulani Rudolf Maseko is a Swaziland human rights lawyer. He was born at Luhleko, a place near Bhunya in Swaziland's Manzini Region.
On 18 March 2014, Thulani was jailed for contempt of court after criticising Swaziland's judicial system.
In April 2014 PUDEMO General Secretary Mlungisi Makhanya was arrested for wearing a party T-shirt to protest the incarceration of Thulani Maseko and journalist Bheki Makhubu.
In August 2014, Maseko wrote to US President Barack Obama from prison, seeking his intervention ahead of the 2014 United States–Africa Leaders Summit.
Maseko was released from prison on 30 July 2015. He had been declared a prisoner of conscience by Amnesty International.