Routes of
administration Oral PubChem CID 71587953 3D model (Jmol) Interactive image ChemSpider ID 32056950 | CAS Number 1234423-95-0 Formula C50H66Cl4N8O10S2 Molar mass 1,145.046 g/mol | |
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Tenapanor is a drug developed by Ardelyx, which acts as an inhibitor of the sodium-proton exchanger NHE3. This antiporter protein is found in the kidney and intestines, and normally acts to regulate the levels of sodium absorbed and secreted by the body. When administered orally, tenapanor selectively inhibits sodium uptake in the intestines, limiting the amount absorbed from food, and thereby reduces levels of sodium in the body. This may make it useful in the treatment of chronic kidney disease and hypertension, both of which are exacerbated by excess sodium in the diet.
References
Tenapanor Wikipedia(Text) CC BY-SA