Samiksha Jaiswal (Editor)

Taurochenodeoxycholate 6α hydroxylase

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EC number
  
1.14.13.97

IntEnz
  
IntEnz view

ExPASy
  
NiceZyme view

CAS number
  
105669-85-0

BRENDA
  
BRENDA entry

KEGG
  
KEGG entry

Taurochenodeoxycholate 6alpha-hydroxylase (EC 1.14.13.97, CYP3A4, CYP4A21, taurochenodeoxycholate 6alpha-monooxygenase) is an enzyme with systematic name taurochenodeoxycholate,NADPH:oxygen oxidoreductase (6alpha-hydroxylating). This enzyme catalyses the following chemical reaction

(1) taurochenodeoxycholate + NADPH + H+ + O2 ⇌ taurohyocholate + NADP+ + H2O (2) lithocholate + NADPH + H+ + O2 ⇌ hyodeoxycholate + NADP+ + H2O

Taurochenodeoxycholate 6α-hydroxylase is a heme-thiolate protein (P-450).

References

Taurochenodeoxycholate 6α-hydroxylase Wikipedia
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